diff --git a/src/audio_core/dsp_interface.cpp b/src/audio_core/dsp_interface.cpp
index 00c8dd65d..74ab37f54 100644
--- a/src/audio_core/dsp_interface.cpp
+++ b/src/audio_core/dsp_interface.cpp
@@ -86,7 +86,7 @@ void DspInterface::OutputCallback(s16* buffer, std::size_t num_frames) {
 
     // Implementation of the hardware volume slider
     // A cubic curve is used to approximate a linear change in human-perceived loudness
-    const float linear_volume = std::clamp(Settings::values.volume, 0.0f, 1.0f);
+    const float linear_volume = std::clamp(Settings::Volume(), 0.0f, 1.0f);
     if (linear_volume != 1.0) {
         const float volume_scale_factor = linear_volume * linear_volume * linear_volume;
         for (std::size_t i = 0; i < num_frames; i++) {
diff --git a/src/citra_qt/configuration/config.cpp b/src/citra_qt/configuration/config.cpp
index b4dcd4759..52dc5c852 100644
--- a/src/citra_qt/configuration/config.cpp
+++ b/src/citra_qt/configuration/config.cpp
@@ -58,7 +58,7 @@ const std::array<std::array<int, 5>, Settings::NativeAnalog::NumAnalogs> Config:
 // This must be in alphabetical order according to action name as it must have the same order as
 // UISetting::values.shortcuts, which is alphabetically ordered.
 // clang-format off
-const std::array<UISettings::Shortcut, 23> default_hotkeys{
+const std::array<UISettings::Shortcut, 24> default_hotkeys{
     {{QStringLiteral("Advance Frame"),            QStringLiteral("Main Window"), {QStringLiteral("\\"), Qt::ApplicationShortcut}},
      {QStringLiteral("Capture Screenshot"),       QStringLiteral("Main Window"), {QStringLiteral("Ctrl+P"), Qt::ApplicationShortcut}},
      {QStringLiteral("Continue/Pause Emulation"), QStringLiteral("Main Window"), {QStringLiteral("F4"), Qt::WindowShortcut}},
@@ -70,6 +70,7 @@ const std::array<UISettings::Shortcut, 23> default_hotkeys{
      {QStringLiteral("Load Amiibo"),              QStringLiteral("Main Window"), {QStringLiteral("F2"), Qt::ApplicationShortcut}},
      {QStringLiteral("Load File"),                QStringLiteral("Main Window"), {QStringLiteral("Ctrl+O"), Qt::WindowShortcut}},
      {QStringLiteral("Load from Newest Slot"),    QStringLiteral("Main Window"), {QStringLiteral("Ctrl+V"), Qt::WindowShortcut}},
+     {QStringLiteral("Mute Audio"),               QStringLiteral("Main Window"), {QStringLiteral("Ctrl+M"), Qt::WindowShortcut}},
      {QStringLiteral("Remove Amiibo"),            QStringLiteral("Main Window"), {QStringLiteral("F3"), Qt::ApplicationShortcut}},
      {QStringLiteral("Restart Emulation"),        QStringLiteral("Main Window"), {QStringLiteral("F6"), Qt::WindowShortcut}},
      {QStringLiteral("Rotate Screens Upright"),   QStringLiteral("Main Window"), {QStringLiteral("F8"), Qt::WindowShortcut}},
diff --git a/src/citra_qt/main.cpp b/src/citra_qt/main.cpp
index b10003dbd..637937a06 100644
--- a/src/citra_qt/main.cpp
+++ b/src/citra_qt/main.cpp
@@ -596,6 +596,9 @@ void GMainWindow::InitializeHotkeys() {
             &QShortcut::activated, ui->action_Load_from_Newest_Slot, &QAction::trigger);
     connect(hotkey_registry.GetHotkey(main_window, QStringLiteral("Save to Oldest Slot"), this),
             &QShortcut::activated, ui->action_Save_to_Oldest_Slot, &QAction::trigger);
+    connect(hotkey_registry.GetHotkey(main_window, QStringLiteral("Mute Audio"), this),
+            &QShortcut::activated, this,
+            [] { Settings::values.audio_muted = !Settings::values.audio_muted; });
 }
 
 void GMainWindow::ShowUpdaterWidgets() {
diff --git a/src/core/settings.cpp b/src/core/settings.cpp
index 3a26e7217..913dd01ed 100644
--- a/src/core/settings.cpp
+++ b/src/core/settings.cpp
@@ -131,6 +131,13 @@ void LogSettings() {
     log_setting("Debugging_GdbstubPort", values.gdbstub_port);
 }
 
+float Volume() {
+    if (values.audio_muted) {
+        return 0.0f;
+    }
+    return values.volume;
+}
+
 void LoadProfile(int index) {
     Settings::values.current_input_profile = Settings::values.input_profiles[index];
     Settings::values.current_input_profile_index = index;
diff --git a/src/core/settings.h b/src/core/settings.h
index b7d35e070..518f1a8eb 100644
--- a/src/core/settings.h
+++ b/src/core/settings.h
@@ -210,6 +210,7 @@ struct Values {
     bool use_vsync_new;
 
     // Audio
+    bool audio_muted;
     bool enable_dsp_lle;
     bool enable_dsp_lle_multithread;
     std::string sink_id;
@@ -244,6 +245,8 @@ struct Values {
     u64 audio_bitrate;
 } extern values;
 
+float Volume();
+
 // a special value for Values::region_value indicating that citra will automatically select a region
 // value to fit the region lockout info of the game
 static constexpr int REGION_VALUE_AUTO_SELECT = -1;