diff --git a/src/video_core/buffer_cache/buffer_cache.h b/src/video_core/buffer_cache/buffer_cache.h
index 06fd40851..e6414df78 100644
--- a/src/video_core/buffer_cache/buffer_cache.h
+++ b/src/video_core/buffer_cache/buffer_cache.h
@@ -1938,14 +1938,20 @@ typename BufferCache<P>::Binding BufferCache<P>::StorageBufferBinding(GPUVAddr s
                                                                       bool is_written) const {
     const GPUVAddr gpu_addr = gpu_memory->Read<u64>(ssbo_addr);
     const u32 size = gpu_memory->Read<u32>(ssbo_addr + 8);
-    const std::optional<VAddr> cpu_addr = gpu_memory->GpuToCpuAddress(gpu_addr);
+    const u32 alignment = runtime.GetStorageBufferAlignment();
+
+    const GPUVAddr aligned_gpu_addr = Common::AlignDown(gpu_addr, alignment);
+    const u32 aligned_size = Common::AlignUp(static_cast<u32>(gpu_addr - aligned_gpu_addr) + size, alignment);
+
+    const std::optional<VAddr> cpu_addr = gpu_memory->GpuToCpuAddress(aligned_gpu_addr);
     if (!cpu_addr || size == 0) {
         return NULL_BINDING;
     }
-    const VAddr cpu_end = Common::AlignUp(*cpu_addr + size, Core::Memory::YUZU_PAGESIZE);
+
+    const VAddr cpu_end = Common::AlignUp(*cpu_addr + aligned_size, Core::Memory::YUZU_PAGESIZE);
     const Binding binding{
         .cpu_addr = *cpu_addr,
-        .size = is_written ? size : static_cast<u32>(cpu_end - *cpu_addr),
+        .size = is_written ? aligned_size : static_cast<u32>(cpu_end - *cpu_addr),
         .buffer_id = BufferId{},
     };
     return binding;
diff --git a/src/video_core/renderer_opengl/gl_buffer_cache.h b/src/video_core/renderer_opengl/gl_buffer_cache.h
index a8c3f8b67..bb1962073 100644
--- a/src/video_core/renderer_opengl/gl_buffer_cache.h
+++ b/src/video_core/renderer_opengl/gl_buffer_cache.h
@@ -160,6 +160,10 @@ public:
         return device.CanReportMemoryUsage();
     }
 
+    u32 GetStorageBufferAlignment() const {
+        return static_cast<u32>(device.GetShaderStorageBufferAlignment());
+    }
+
 private:
     static constexpr std::array PABO_LUT{
         GL_VERTEX_PROGRAM_PARAMETER_BUFFER_NV,          GL_TESS_CONTROL_PROGRAM_PARAMETER_BUFFER_NV,
diff --git a/src/video_core/renderer_opengl/gl_shader_cache.cpp b/src/video_core/renderer_opengl/gl_shader_cache.cpp
index 03b6314ff..01e0cddb6 100644
--- a/src/video_core/renderer_opengl/gl_shader_cache.cpp
+++ b/src/video_core/renderer_opengl/gl_shader_cache.cpp
@@ -236,6 +236,7 @@ ShaderCache::ShaderCache(RasterizerOpenGL& rasterizer_, Core::Frontend::EmuWindo
           .needs_demote_reorder = device.IsAmd(),
           .support_snorm_render_buffer = false,
           .support_viewport_index_layer = device.HasVertexViewportLayer(),
+          .min_ssbo_alignment = static_cast<u32>(device.GetShaderStorageBufferAlignment()),
       } {
     if (use_asynchronous_shaders) {
         workers = CreateWorkers();
diff --git a/src/video_core/renderer_vulkan/vk_buffer_cache.cpp b/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
index 487d8b416..bc78287ce 100644
--- a/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
+++ b/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
@@ -330,6 +330,10 @@ bool BufferCacheRuntime::CanReportMemoryUsage() const {
     return device.CanReportMemoryUsage();
 }
 
+u32 BufferCacheRuntime::GetStorageBufferAlignment() const {
+    return static_cast<u32>(device.GetStorageBufferAlignment());
+}
+
 void BufferCacheRuntime::Finish() {
     scheduler.Finish();
 }
diff --git a/src/video_core/renderer_vulkan/vk_buffer_cache.h b/src/video_core/renderer_vulkan/vk_buffer_cache.h
index 183b33632..06539c733 100644
--- a/src/video_core/renderer_vulkan/vk_buffer_cache.h
+++ b/src/video_core/renderer_vulkan/vk_buffer_cache.h
@@ -73,6 +73,8 @@ public:
 
     bool CanReportMemoryUsage() const;
 
+    u32 GetStorageBufferAlignment() const;
+
     [[nodiscard]] StagingBufferRef UploadStagingBuffer(size_t size);
 
     [[nodiscard]] StagingBufferRef DownloadStagingBuffer(size_t size);
diff --git a/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp b/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
index 4d7770bf8..4aaea0e12 100644
--- a/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
+++ b/src/video_core/renderer_vulkan/vk_pipeline_cache.cpp
@@ -344,6 +344,7 @@ PipelineCache::PipelineCache(RasterizerVulkan& rasterizer_, const Device& device
             driver_id == VK_DRIVER_ID_AMD_PROPRIETARY || driver_id == VK_DRIVER_ID_AMD_OPEN_SOURCE,
         .support_snorm_render_buffer = true,
         .support_viewport_index_layer = device.IsExtShaderViewportIndexLayerSupported(),
+        .min_ssbo_alignment = static_cast<u32>(device.GetStorageBufferAlignment()),
     };
 
     if (device.GetMaxVertexInputAttributes() < Maxwell::NumVertexAttributes) {